Sequence similarity in structurally dissimilar proteins
نویسندگان
چکیده
منابع مشابه
Sequence similarity in structurally dissimilar proteins
It is a central tenet of protein evolution that the threedimensional structure of a protein family is better conserved than the sequences themselves. So structural similarities between related proteins should be detectable over longer evolutionary distances and be most useful for the functional prediction of proteins without closely related homologs. Comparative sequence and structural analysis...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2003
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(03)00070-8